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ERO1L 抗体 (AA 321-420) (HRP)

This anti-ERO1L antibody is a 兔 多克隆 antibody detecting ERO1L in WB 和 ELISA. Suitable for 人.
产品编号 ABIN5675521
发货至: 中国

Quick Overview for ERO1L 抗体 (AA 321-420) (HRP) (ABIN5675521)

抗原

See all ERO1L 抗体
ERO1L (ERO1-Like Protein alpha (ERO1L))

适用

  • 38
  • 4
  • 4

宿主

  • 32
  • 5
  • 1

克隆类型

  • 35
  • 2
多克隆

标记

  • 21
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ERO1L antibody is conjugated to HRP

应用范围

  • 38
  • 16
  • 16
  • 14
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 321-420

    交叉反应

    预测反应

    Mouse,Rat,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ERO1L

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ERO1L (ERO1-Like Protein alpha (ERO1L))

    别名

    ERO1L

    背景

    Synonyms: ERO1-like protein alpha, ERO1A, ERO1-L, ERO1-L-alpha, Endoplasmic oxidoreductin-1-like protein, Endoplasmic reticulum oxidoreductase alpha, Oxidoreductin-1-L-alpha, ERO1L

    Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.

    基因ID

    30001

    UniProt

    Q96HE7

    途径

    Peptide Hormone Metabolism, ER-Nucleus Signaling, Brown Fat Cell Differentiation
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