DUSP11 抗体 (C-Term)
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Quick Overview for DUSP11 抗体 (C-Term) (ABIN5673780)
抗原
See all DUSP11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- HTQTQSLQQS VRKFSENPHV YQRHHLPPPG PPGEDYSHRR YSWNVKPNAS
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DUSP11
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DUSP11 (Dual Specificity Phosphatase 11 (RNA/RNP Complex 1-Interacting) (DUSP11))
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别名
- DUSP11
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背景
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The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.
Alias Symbols: PIR1
Protein Size: 330 -
基因ID
- 8446
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NCBI登录号
- NM_003584, NP_003575
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UniProt
- O75319
抗原
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