TMEM43 抗体 (N-Term)
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Quick Overview for TMEM43 抗体 (N-Term) (ABIN5673734)
抗原
See all TMEM43 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ANYSSTSTRR EHVKVKTSSQ PGFLERLSET SGGMFVGLMA FLLSFYLIFT
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TMEM43
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TMEM43 (Transmembrane Protein 43 (TMEM43))
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别名
- TMEM43
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背景
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This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.
Alias Symbols: LUMA, ARVC5, ARVD5, EDMD7
Protein Size: 400 -
基因ID
- 79188
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NCBI登录号
- NM_024334, NP_077310
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UniProt
- Q9BTV4
抗原
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