PLSCR3 抗体 (N-Term)
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Quick Overview for PLSCR3 抗体 (N-Term) (ABIN5673452)
抗原
See all PLSCR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- PPKGYAPSPP PPYPVTPGYP EPALHPGPGQ APVPAQVPAP APGFALFPSP
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PLSCR3
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
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别名
- PLSCR3
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背景
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May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.
Protein Size: 295 -
基因ID
- 57048
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NCBI登录号
- NM_001201576, NP_001188505
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UniProt
- Q9NRY6
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途径
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
抗原
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