SNAPIN 抗体 (C-Term)
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Quick Overview for SNAPIN 抗体 (C-Term) (ABIN5672645)
抗原
See all SNAPIN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LLNARRRVVL VNNILQNAQE RLRRLNHSVA KETARRRAML DSGIYPPGSP
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human SNAPIN
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SNAPIN (SNAP-Associated Protein (SNAPIN))
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别名
- SNAPIN
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背景
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The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.
Alias Symbols: BLOS7, SNAPAP, BLOC1S7
Protein Size: 136 -
基因ID
- 23557
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NCBI登录号
- NM_012437, NP_036569
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UniProt
- O95295
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途径
- Synaptic Membrane, Synaptic Vesicle Exocytosis
抗原
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