CDC14B 抗体 (N-Term)
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北京 101111
Quick Overview for CDC14B 抗体 (N-Term) (ABIN5672445)
抗原
See all CDC14B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- KRKSERRSSW AAAPPCSRRC SSTSPGVKKI RSSTQQDPRR RDPQDDVYLD
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CDC14B
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))
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别名
- CDC14B
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背景
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The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Alias Symbols: CDC14B3, Cdc14B1, Cdc14B2, hCDC14B
Protein Size: 498 -
基因ID
- 8555
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NCBI登录号
- NM_001077181, NP_001070649
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UniProt
- O60729
抗原
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