AGO1 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for AGO1 抗体 (C-Term) (ABIN5672142)
抗原
See all AGO1 (EIF2C1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- RSVSIPAPAY YARLVAFRAR YHLVDKEHDS GEGSHISGQS NGRDPQALAK
-
纯化方法
- Affinity purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2C1
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))
-
别名
- EIF2C1
-
背景
-
This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.
Alias Symbols: Q99, EIF2C, hAgo1, EIF2C1, GERP95
Protein Size: 857 -
基因ID
- 26523
-
NCBI登录号
- NM_012199, NP_036331
-
UniProt
- Q9UL18
-
途径
- Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Transport, Regulation of Actin Filament Polymerization, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization
抗原
-