PRUNE2 抗体 (C-Term)
The 兔 多克隆 anti-PRUNE2 antibody is suitable to detect PRUNE2 in samples from 人. It has been validated for WB.
产品编号 ABIN5671800
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for PRUNE2 抗体 (C-Term) (ABIN5671800)
抗原
See all PRUNE2 抗体
PRUNE2
(Prune Homolog 2 (PRUNE2))
适用
人
宿主
兔
克隆类型
多克隆
标记
This PRUNE2 antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- C-Term
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序列
- LNDTHPRRIK LTAPNINLSL DQSEGSILSD DNLDSPDEID INVDELDTPD
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PRUNE2
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anti-Prune Homolog 2 (PRUNE2) (AA 1-250) antibody
PRUNE2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prune Homolog 2 (PRUNE2) (Internal Region) antibodyVerified PRUNE2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PRUNE2 (Prune Homolog 2 (PRUNE2))
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别名
- PRUNE2
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背景
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The protein encoded by this gene belongs to the B-cell CLL/lymphoma 2 and adenovirus E1B 19 kDa interacting family, whose members play roles in many cellular processes including apotosis, cell transformation, and synaptic function. Several functions for this protein have been demonstrated including suppression of Ras homolog family member A activity, which results in reduced stress fiber formation and suppression of oncogenic cellular transformation. A high molecular weight isoform of this protein has also been shown to colocalize with Adaptor protein complex 2, beta-Adaptin and endodermal markers, suggesting an involvement in post-endocytic trafficking. In prostate cancer cells, this gene acts as a tumor suppressor and its expression is regulated by prostate cancer antigen 3, a non-protein coding gene on the opposite DNA strand in an intron of this gene. Prostate cancer antigen 3 regulates levels of this gene through formation of a double-stranded RNA that undergoes adenosine deaminase actin on RNA-dependent adenosine-to-inosine RNA editing. Alternative splicing results in multiple transcript variants.
Alias Symbols: BMCC1, BNIPXL, C9orf65, KIAA0367
Protein Size: 352 -
基因ID
- 158471
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NCBI登录号
- NM_001308047, NP_001294976
抗原
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