SPG21 抗体 (N-Term)
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北京 101111
Quick Overview for SPG21 抗体 (N-Term) (ABIN5671445)
抗原
See all SPG21 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GTVPLKKIIV DDDDSKIWSL YDAGPRSIRC PLIFLPPVSG TADVFFRQIL
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of Human SPG21
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anti-Spastic Paraplegia 21 (SPG21) (AA 1-308) antibody
SPG21 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spastic Paraplegia 21 (SPG21) (AA 211-306) antibodySPG21 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Spastic Paraplegia 21 (SPG21) (AA 211-306) antibodySPG21 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SPG21 (Spastic Paraplegia 21 (SPG21))
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别名
- SPG21
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背景
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The protein encoded by this gene binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. Mutations in this gene are associated with autosomal recessive spastic paraplegia 21 (SPG21), also known as mast syndrome. Alternative splicing results in multiple transcript variants.
Alias Symbols: MAST, ACP33, GL010, BM-019
Protein Size: 281 -
基因ID
- 51324
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NCBI登录号
- NM_001127889, NP_001121361
抗原
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