PHOX2B 抗体 (C-Term)
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北京 101111
Quick Overview for PHOX2B 抗体 (C-Term) (ABIN5671377)
抗原
See all PHOX2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- PHOX2B Antibody - C-terminal region
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序列
- RAAAAAAAAA KNGSSGKKSD SSRDDESKEA KSTDPDSTGG PGPNPNPTPS
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产品特性
- This is a rabbit polyclonal antibody against PHX2B. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human PHX2B
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74127-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PHOX2B (Paired-Like Homeobox 2b (PHOX2B))
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别名
- PHOX2B
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背景
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Background Information: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.
Gene Name: paired like homeobox 2B
Alternative Symbols: CCHS, PMX2B, NBLST2, NBPhox
Protein Name: paired mesoderm homeobox protein 2B
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分子量
- 34kDa
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基因ID
- 8929
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NCBI登录号
- NP_003915
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UniProt
- Q99453
抗原
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