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COMMD1 抗体 (AA 1-190)

Name: COMMD1 抗体 (AA 1-190)
SKU: ABIN566862
Availability: OutOfStock

This anti-COMMD1 antibody is a 小鼠单克隆 antibody detecting COMMD1 in WB, ELISA 和 IP. Suitable for 人. This Primary Antibody has been cited in 9+ publications.

COMMD1 monoclonal antibody (M01), clone 2A12 Western Blot analysis of COMMD1 expression in HeLa . (COMMD1 抗体 (AA 1-190))

Detection limit for recombinant GST tagged COMMD1 is approximately 0. (COMMD1 抗体 (AA 1-190))

ELISA

Immunoprecipitation of COMMD1 transfected lysate using anti-COMMD1 monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with COMMD1 MaxPab rabbit polyclonal antibody. (COMMD1 抗体 (AA 1-190))

Western Blot analysis of COMMD1 expression in transfected 293T cell line by COMMD1 monoclonal antibody (M01), clone 2A12. (COMMD1 抗体 (AA 1-190))

Western Blot detection against Immunogen (46. (COMMD1 抗体 (AA 1-190))

COMMD1 monoclonal antibody (M01), clone 2A12. (COMMD1 抗体 (AA 1-190))

6 images

(9 references)

产品编号 ABIN566862

发货至: 中国

Datasheet as PDF

Quick Overview for COMMD1 抗体 (AA 1-190) (ABIN566862)

抗原

See all COMMD1 抗体

COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This COMMD1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunoprecipitation (IP)

克隆位点

2A12

抗原表位
15

7

7

4

4

2

1

1

1

1

1
AA 1-190

原理

Mouse monoclonal antibody raised against a full length recombinant COMMD1.

序列

MAAGELEGGK PLSGLLNALA QDTFHGYPGI TEELLRSQLY PEVPPEEFRP FLAKMRGILK SIASADMDFN QLEAFLTAQT KKQGGITSDQ AAVISKFWKS HKTKIRESLM NQSRWNSGLR GLSWRVDGKS QSRHSAQIHT PVAIIELELG KYGQESEFLC LEFDEVKVNQ ILKTLSEVEE SISTLISQPN

交叉反应

人

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

COMMD1 (AAH22046.1, 1 a.a. ~ 190 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

亚型

IgG2a
anti-Copper Metabolism (Murr1) Domain Containing 1 (COMMD1) antibody
COMMD1 适用: 人, 猴 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3B3 unconjugated

anti-Copper Metabolism (Murr1) Domain Containing 1 (COMMD1) antibody
COMMD1 适用: 人 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated

anti-Copper Metabolism (Murr1) Domain Containing 1 (COMMD1) (AA 1-190) antibody
COMMD1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Copper Metabolism (Murr1) Domain Containing 1 (COMMD1) (AA 1-190) antibody
COMMD1 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 2B12 unconjugated

anti-Copper Metabolism (Murr1) Domain Containing 1 (COMMD1) (AA 2-190) antibody
COMMD1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Copper Metabolism (Murr1) Domain Containing 1 (COMMD1) (AA 1-190) antibody
COMMD1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-Copper Metabolism (Murr1) Domain Containing 1 (COMMD1) antibody
COMMD1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated

anti-Copper Metabolism (Murr1) Domain Containing 1 (COMMD1) (AA 1-190) antibody
COMMD1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Copper Metabolism (Murr1) Domain Containing 1 (COMMD1) (Internal Region) antibody
COMMD1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Copper Metabolism (Murr1) Domain Containing 1 (COMMD1) antibody
COMMD1 适用: 人 WB 宿主: 兔 Polyclonal RB54338 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
OHara, Simpson, Morin, Loveridge, Williams, Novo, Stark: "p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-?B subunit." in: Journal of cell science, Vol. 127, Issue Pt 17, pp. 3659-65, (2014) (PubMed).

Schilling, Bayer, Li, Molls, Vaupel, Multhoff: "Radiosensitization of normoxic and hypoxic h1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1?." in: PLoS ONE, Vol. 7, Issue 2, pp. e31110, (2012) (PubMed).

Drévillon, Tanguy, Hinzpeter, Arous, de Becdelièvre, Aissat, Tarze, Goossens, Fanen: "COMMD1-mediated ubiquitination regulates CFTR trafficking." in: PLoS ONE, Vol. 6, Issue 3, pp. e18334, (2011) (PubMed).

Vonk, Wijmenga, Berger, van de Sluis, Klomp: "Cu,Zn superoxide dismutase maturation and activity are regulated by COMMD1." in: The Journal of biological chemistry, Vol. 285, Issue 37, pp. 28991-9000, (2010) (PubMed).

Huang, Wu, Li: "Tumor suppressor ARF promotes non-classic proteasome-independent polyubiquitination of COMMD1." in: The Journal of biological chemistry, Vol. 283, Issue 17, pp. 11453-60, (2008) (PubMed).

Burkhead, Morgan, Shinde, Haddock, Lutsenko: "COMMD1 forms oligomeric complexes targeted to the endocytic membranes via specific interactions with phosphatidylinositol 4,5-bisphosphate." in: The Journal of biological chemistry, Vol. 284, Issue 1, pp. 696-707, (2008) (PubMed).

Weiss, Lozoya, Tuma, Gotthardt, Reichert, Ehehalt, Stremmel, Füllekrug: "Copper-induced translocation of the Wilson disease protein ATP7B independent of Murr1/COMMD1 and Rab7." in: The American journal of pathology, Vol. 173, Issue 6, pp. 1783-94, (2008) (PubMed).

Maine, Mao, Komarck, Burstein: "COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase." in: The EMBO journal, Vol. 26, Issue 2, pp. 436-47, (2007) (PubMed).

de Bie, van de Sluis, Burstein, van de Berghe, Muller, Berger, Gitlin, Wijmenga, Klomp: "Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B." in: Gastroenterology, Vol. 133, Issue 4, pp. 1316-26, (2007) (PubMed).
抗原

COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))

别名

COMMD1

背景

Full Gene Name: copper metabolism (Murr1) domain containing 1
Synonyms: C2orf5,MGC27155,MURR1

基因ID

150684

途径

Transition Metal Ion Homeostasis