Recombinant CD33 (Gemtuzumab Biosimilar) 抗体
This anti-CD33 (Gemtuzumab Biosimilar) antibody is a 兔 Chimeric antibody detecting CD33 (Gemtuzumab Biosimilar) in FACS 和 IF. Suitable for 人.
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Quick Overview for Recombinant CD33 (Gemtuzumab Biosimilar) 抗体 (ABIN5668211)
抗原
CD33 (Gemtuzumab Biosimilar)
抗体类型
Recombinant Antibody
适用
人
宿主
兔
克隆类型
Chimeric
标记
This CD33 (Gemtuzumab Biosimilar) antibody is un-conjugated
应用范围
Flow Cytometry (FACS), Immunofluorescence (IF)
克隆位点
HP67-6
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原理
- Anti-CD33 [hP67.6 (Gemtuzumab)], Rabbit IgG, kappa
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特异性
- Recognises human CD33.
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产品特性
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Original Species of Ab: Human
Original Format of Ab: IgG4
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纯化方法
- Protein A affinity purified
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纯度
- > 98 % as determined by SDS-PAGE
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内毒素水平
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
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免疫原
- Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
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亚型
- IgG kappa
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anti-CD33 (Gemtuzumab Biosimilar) antibody
Research Grade 适用: 人 FACS 宿主: Humanized Monoclonal unconjugated Recombinant Antibody
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应用备注
- A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD33 (Gemtuzumab Biosimilar)
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物质类
- Biosimilar
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背景
- Siglec-3
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UniProt
- P20138
抗原
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