Recombinant CD33 (Gemtuzumab Biosimilar) 抗体
Quick Overview for Recombinant CD33 (Gemtuzumab Biosimilar) 抗体 (ABIN5668210)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Anti-CD33 [hP67.6 (Gemtuzumab)], Human IgG4, kappa
-
特异性
- Recognises human CD33.
-
产品特性
-
Original Species of Ab: Human
Original Format of Ab: IgG4
-
纯化方法
- Protein A affinity purified
-
纯度
- > 98 % as determined by SDS-PAGE
-
内毒素水平
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
-
免疫原
- Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
-
亚型
- IgG4 kappa
-
-
anti-CD33 (Gemtuzumab Biosimilar) antibody
Research Grade 适用: 人 FACS 宿主: Humanized Monoclonal unconjugated Recombinant Antibody
anti-CD33 (Gemtuzumab Biosimilar) antibody适用: 人 FACS, IF 宿主: 兔 Chimeric HP67-6 unconjugated Recombinant Antibody
-
-
应用备注
- A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % Proclin 300.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
-
- CD33 (Gemtuzumab Biosimilar)
-
物质类
- Biosimilar
-
背景
- Siglec-3
-
UniProt
- P20138
抗原
-
