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Recombinant CD32/CD16 抗体

This anti-CD32/CD16 antibody is a 大鼠 单克隆 antibody detecting CD32/CD16 in FACS, IP, IF, BR 和 IHC. Suitable for 小鼠.
产品编号 ABIN5668180
发货至: 中国

Quick Overview for Recombinant CD32/CD16 抗体 (ABIN5668180)

抗原

CD32/CD16

抗体类型

Recombinant Antibody

适用

小鼠

宿主

  • 40
  • 1
  • 1
大鼠

克隆类型

  • 38
  • 1
  • 1
单克隆

标记

  • 11
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD32/CD16 antibody is un-conjugated

应用范围

  • 41
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Blocking Reagent (BR), Immunohistochemistry (IHC)

克隆位点

2-4G2
  • 原理

    Anti-CD16/CD32 [2.4G2], Rat IgG2b, kappa

    特异性

    This antibody binds to an epitope on the extracellular domains of the mouse FcγIII and FcγII, thereby inhibiting their ability to bind antibodies via their Fc region. receptors. Also binding the FcγI receptor (CD64) via its Fc domain.

    产品特性

    Original Species of Ab: Rat

    Original Format of Ab: IgG2b

    纯化方法

    Protein A affinity purified

    免疫原

    Mouse BALB/c Macrophage J774 Cell Line.

    亚型

    IgG2b kappa
  • 应用备注

    This antibody binds murine Fc Receptors CD16/CD32 and inhibits binding of antibodies to these. It can therefore be used as an Fc-blocking reagent, to reduce non-specific staining of cells by antibodies binding via their Fc-region. A similar effect can be achieved using the Fc Silent range of antibodies made by Absolute Antibody that prevent these interactions at the level of the Fc receptor binding site, which has been mutated to lack affinity for the Fc receptors.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD32/CD16

    别名

    CD16/CD32

    背景

    Fcγ III/II Receptor, Low affinity immunoglobulin gamma Fc region receptor III, IgG Fc receptor III, Fc-gamma RIII, FcRIII, CD16, Low affinity immunoglobulin gamma Fc region receptor II, Fc gamma receptor IIB, Fc-gamma RII, Fc-gamma-RIIB, FcRII IgG Fc rec

    UniProt

    P08508, P08101
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