Recombinant TNF alpha (Infliximab Biosimilar) 抗体
This anti-TNF alpha (Infliximab Biosimilar) antibody is a 兔 Chimeric antibody detecting TNF alpha (Infliximab Biosimilar) in FACS, in vivo 和 ELISA. Suitable for 人.
Quick Overview for Recombinant TNF alpha (Infliximab Biosimilar) 抗体 (ABIN5668148)
抗原
TNF alpha (Infliximab Biosimilar)
抗体类型
Recombinant Antibody
适用
人
宿主
兔
克隆类型
Chimeric
标记
This TNF alpha (Infliximab Biosimilar) antibody is un-conjugated
应用范围
Flow Cytometry (FACS), In vivo Studies (in vivo), ELISA
克隆位点
CA2
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原理
- Anti-TNF alpha [cA2 (Infliximab)], Rabbit IgG, kappa
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特异性
- Binds to soluble and transmembrane forms of TNF-alpha and neutralizes its biological activity. Does not bind to TNF-beta.
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产品特性
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Original Species of Ab: Human
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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纯度
- > 98 % as determined by SDS-PAGE
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内毒素水平
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
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免疫原
- Purified recombinant human TNF (rTNF).
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亚型
- IgG kappa
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anti-TNF alpha (Infliximab Biosimilar) antibody
适用: 人 FACS, in vivo, ELISA 宿主: Human Chimeric cA2 unconjugated Recombinant Antibody
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应用备注
- This antibody can be used to detect and neutralize human TNF alpha. Unlike Adalimumab (Ab00718), Infliximab does not bind to mouse TNF alpha (Arnoult 2017, PMID: 28584008).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- TNF alpha (Infliximab Biosimilar)
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物质类
- Biosimilar
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背景
- TNF-α, TNFα, TNFSF, Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, TNFa
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UniProt
- P01375
抗原
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