Recombinant EGFR (Matuzumab Biosimilar) 抗体 (Extracellular Domain)
适用: 人
FACS, WB, BR
宿主: 兔
Chimeric
unconjugated
Recombinant Antibody
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- 抗原 See all EGFR (Matuzumab Biosimilar) products
- EGFR (Matuzumab Biosimilar)
- 抗体类型
- Recombinant Antibody
- 抗原表位
- Extracellular Domain
- 适用
- 人
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宿主
- 兔
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克隆类型
- Chimeric
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标记
- This EGFR (Matuzumab Biosimilar) antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Western Blotting (WB), Blocking Reagent (BR)
- 特异性
- Binds to human EGFR.
- 产品特性
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OriginalSpeciesName: Human
OriginalFormat: IgG1
- 纯化方法
- Purified antibody.
- 纯度
- > 98 % as determined by SDS-PAGE
- 内毒素水平
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- 免疫原
- The parental mouse antibody was generated by immunizing BALB/c mice intraperitoneally with A431 cells in phosphate buffered saline (PBS). Later on the humanzied version of the antibody was created by grafting CDRs of the murine antibody onto human constant regions.
- 亚型
- IgG kappa
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anti-EGFR (Matuzumab Biosimilar) (Extracellular Domain) antibody
适用: 人 FACS, WB, BR 宿主: Human Monoclonal unconjugated Recombinant Antibody
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- 应用备注
- This antibody binds to human EGFR at a side distinct frm the antigen binding site, preventing conformational re-arrangement required for dimerization, a process essential for high-affinitiy ligand binding (Schmiedel 2008).
- 说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % Proclin 300.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- 抗原
- EGFR (Matuzumab Biosimilar)
- Abstract
- EGFR (Matuzumab Biosimilar) 产品
- 背景
- ErbB-1, ERBB1, HER1, EGF, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EMD72000, mAb425, 425, mAb 425
- UniProt
- P00533
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