Recombinant Polysialic Acid 抗体
This 兔 Chimeric antibody specifically detects Polysialic Acid in FACS, IHC, IP 和 WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN5668053
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Recombinant Polysialic Acid 抗体 (ABIN5668053)
抗原
Polysialic Acid
抗体类型
Recombinant Antibody
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
Chimeric
标记
非结合性
应用范围
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
克隆位点
735
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原理
- Anti-Polysialic acid [735], Rabbit IgG, kappa
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特异性
- Recognises Polysialic acid (PSA), a carbohydrate polymer attached to the neural cell adhesion molecule (NCAM), which shares molecular epitopes with homopolymers of α2,8-linked sialic acid of Escherichia coli K1.
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交叉反应
- 小鼠, 大鼠
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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纯化方法
- Protein A affinity purified
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免疫原
- Homopolymers of alpha2,8-linked sialic acid of Escherichia coli K1.
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亚型
- IgG kappa
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应用备注
- Clone 735 was used for immunostaining and immunoprecipitation in an experimental setup involving antigen preparation from PBMC (Peripheral Blood Mononuclear Cells) (Husmann et al., 1989, PMID: 2529126). This antibody recognises an unusual postranslational modification on neural cell adhesion molecules important in synaptogenesis, oncogenesis (particularly small-cell lung cancer) and development of organs such as the kidney (studied in rats, Lackie et al., 1990). 735 was used for Western blot analysis of PSA-NCAM (Polysialylated Neural Cell Adhesion Molecule) (Charter et al., 2000, PMID: 11030751). In addition to various studies on human cells, the antibody, has also been used the study the fine-composition of poly-sialic acid composition in mice (Galuska et al., 2006).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Polysialic Acid
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背景
- PSA, N-CAM, neural cell adhesion molecule, polySA
抗原
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