Recombinant ITGAL (Efalizumab Biosimilar) 抗体
This anti-ITGAL (Efalizumab Biosimilar) antibody is a 兔 Chimeric antibody detecting ITGAL (Efalizumab Biosimilar) in BR 和 FACS. Suitable for 人.
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Quick Overview for Recombinant ITGAL (Efalizumab Biosimilar) 抗体 (ABIN5668045)
抗原
ITGAL (Efalizumab Biosimilar)
抗体类型
Recombinant Antibody
适用
人
宿主
兔
克隆类型
Chimeric
标记
This ITGAL (Efalizumab Biosimilar) antibody is un-conjugated
应用范围
Blocking Reagent (BR), Flow Cytometry (FACS)
克隆位点
Hu1124
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原理
- Anti-CD11a [hu1124 (Efalizumab)], Rabbit IgG, kappa
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特异性
- Binds to human LFA-1.
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产品特性
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Original Species of Ab: Human
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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纯度
- > 98 % as determined by SDS-PAGE
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内毒素水平
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
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免疫原
- Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.
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亚型
- IgG kappa
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anti-ITGAL (Efalizumab Biosimilar) antibody
适用: 人 BR, FACS 宿主: Human Monoclonal hu1124 unconjugated Recombinant Antibody
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应用备注
- Efalizumab binds to the LFA-1 alpha I domain blocking the ICAM-1 binding site via steric hindrance.
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- ITGAL (Efalizumab Biosimilar)
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物质类
- Biosimilar
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背景
- LFA-1, integrin alpha L
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UniProt
- P20701
抗原
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