Recombinant V alpha TCR 抗体
The 小鼠 单克隆 anti-V alpha TCR antibody (Clone 34) (ABIN5668025) specifically detects V alpha TCR in ELISA, FACS 和 WB.
The antibody is reactive with 人 samples.
产品编号 ABIN5668025
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Recombinant V alpha TCR 抗体 (ABIN5668025)
抗原
V alpha TCR
抗体类型
Recombinant Antibody
适用
人
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
ELISA, Flow Cytometry (FACS), Western Blotting (WB)
克隆位点
34
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原理
- Anti-Vα TCR [34], Mouse IgG1, kappa
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特异性
- This antibody binds to the T-cell receptor alpha chains.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: scFv
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纯化方法
- Protein A affinity purified
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免疫原
- Purified recombinant soluble TCR from the T-cell hybridoma 85.33, corresponding to V alpha 11
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亚型
- IgG1 kappa
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应用备注
- The antibody binds specifically to the recombinant and native variable domain of the α chain which comprises the T-cell receptor (TCR). The TCR is a disulfide-linked heterodimeric protein expressed on the surface of T-cells in complex with CD3 and ζ-chain molecules. The receptor functions in the recognition of MHC molecule and the subsequent activation of T-cells. The monoclonal antibody 34 recognises Vα regions of TCRs expressed in the 85.33 arthritogenic T-cell hybridoma and can be used to analyse TCR V gene expression and for immunotherapy in T cell mediated autoimmunity.
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说明
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This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- V alpha TCR
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背景
- TCR variable alpha chain, T-cell receptor variable alpha chain
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UniProt
- P01848
抗原
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