MAPKBP1 抗体 (AA 1-100)
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北京 101111
Quick Overview for MAPKBP1 抗体 (AA 1-100) (ABIN5664104)
抗原
See all MAPKBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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序列
- MAVEGSTITS RIKNLLRSPS IKLRRSKAGN RREDLSSKVT LEKVLGITVS GGRGLACDPR SGLVAYPAGC VVVLFNPRKH KQHHILNSSR KTITALAFSP
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAPKBP1 (NP_001122080.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))
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别名
- MAPKBP1
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背景
- This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.,MAPKBP1,JNKBP-1,JNKBP1,NPHP20,Signal Transduction,Kinase,MAPKBP1
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分子量
- 23 kDa/109 kDa/134 kDa/149 kDa/163 kDa
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基因ID
- 23005
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UniProt
- O60336
抗原
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