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POT1 抗体 (AA 497-634)

The 兔 多克隆 anti-POT1 antibody is suitable to detect POT1 in samples from 人. It has been validated for WB.
产品编号 ABIN5663924
发货至: 中国
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Quick Overview for POT1 抗体 (AA 497-634) (ABIN5663924)

抗原

See all POT1 抗体
POT1 (Protection of Telomeres 1 (POT1))

适用

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宿主

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克隆类型

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多克隆

标记

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This POT1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 497-634

    序列

    TIHHYGCKQC SSLRSIQNLN SLVDKTSWIP SSVAEALGIV PLQYVFVMTF TLDDGTGVLE AYLMDSDKFF QIPASEVLMD DDLQKSVDMI MDMFCPPGIK IDAYPWLECF IKSYNVTNGT DNQICYQIFD TTVAEDVI

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 497-634 of human POT1 (NP_056265.2).

    亚型

    IgG
  • 应用备注

    WB,1:200 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    POT1 (Protection of Telomeres 1 (POT1))

    别名

    POT1

    背景

    This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.,POT1,CMM10,GLM9,HPOT1,Epigenetics & Nuclear Signaling,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,POT1

    分子量

    60 kDa/71 kDa

    基因ID

    25913

    UniProt

    Q9NUX5

    途径

    Cell Division Cycle, Telomere Maintenance
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