POT1 抗体 (AA 497-634)
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北京 101111
Quick Overview for POT1 抗体 (AA 497-634) (ABIN5663924)
抗原
See all POT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 497-634
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序列
- TIHHYGCKQC SSLRSIQNLN SLVDKTSWIP SSVAEALGIV PLQYVFVMTF TLDDGTGVLE AYLMDSDKFF QIPASEVLMD DDLQKSVDMI MDMFCPPGIK IDAYPWLECF IKSYNVTNGT DNQICYQIFD TTVAEDVI
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 497-634 of human POT1 (NP_056265.2).
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亚型
- IgG
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应用备注
- WB,1:200 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- POT1 (Protection of Telomeres 1 (POT1))
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别名
- POT1
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背景
- This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.,POT1,CMM10,GLM9,HPOT1,Epigenetics & Nuclear Signaling,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,POT1
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分子量
- 60 kDa/71 kDa
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基因ID
- 25913
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UniProt
- Q9NUX5
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途径
- Cell Division Cycle, Telomere Maintenance
抗原
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