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APOB 抗体 (AA 28-330)

The 兔 多克隆 anti-APOB antibody (ABIN5663872) specifically detects APOB in WB 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN5663872
发货至: 中国
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Quick Overview for APOB 抗体 (AA 28-330) (ABIN5663872)

抗原

See all APOB 抗体
APOB (Apolipoprotein B (APOB))

适用

  • 114
  • 27
  • 26
  • 6
  • 2

宿主

  • 79
  • 46
  • 14
  • 2
  • 2

克隆类型

  • 83
  • 59
多克隆

标记

  • 60
  • 24
  • 15
  • 7
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This APOB antibody is un-conjugated

应用范围

  • 85
  • 46
  • 42
  • 31
  • 30
  • 19
  • 17
  • 8
  • 7
  • 6
  • 2
  • 2
  • 1
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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    AA 28-330

    序列

    EEEMLENVSL VCPKDATRFK HLRKYTYNYE AESSSGVPGT ADSRSATRIN CKVELEVPQL CSFILKTSQC TLKEVYGFNP EGKALLKKTK NSEEFAAAMS RYELKLAIPE GKQVFLYPEK DEPTYILNIK RGIISALLVP PETEEAKQVL FLDTVYGNCS THFTVKTRKG NVATEISTER DLGQCDRFKP IRTGISPLAL IKGMTRPLST LISSSQSCQY TLDAKRKHVA EAICKEQHLF LPFSYKNKYG MVAQVTQTLK LEDTPKINSR FFGEGTKKMG LAFESTKSTS PPKQAEAVLK TLQ

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 28-330 of human ApoB (NP_000375.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    APOB (Apolipoprotein B (APOB))

    别名

    APOB

    背景

    This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.,APOB,FLDB,LDLCQ4,apoB-100,apoB-48,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Heart,Lipids,Lipoproteins/Apolipoproteins,Cardiovascular diseases,Heart disease,APOB

    分子量

    515 kDa

    基因ID

    338

    UniProt

    P04114

    途径

    Lipid Metabolism
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