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RXFP1 抗体 (AA 68-162)

Cited in 8+ publications. This 小鼠 单克隆 anti-RXFP1 antibody (Clone 3E3) specifically detects RXFP1 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN566200
发货至: 中国
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Quick Overview for RXFP1 抗体 (AA 68-162) (ABIN566200)

抗原

See all RXFP1 抗体
RXFP1 (Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1))

适用

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宿主

  • 31
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小鼠

克隆类型

  • 33
  • 5
单克隆

标记

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This RXFP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

3E3
  • 抗原表位

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    AA 68-162

    原理

    Mouse monoclonal antibody raised against a partial recombinant LGR7.

    序列

    WSMQFDKYFA SYYKMTSQYP FEAETPECLV GSVPVQCLCQ GLELDCDETN LRAVPSVSSN VTAMSLQWNL IRKLPPDCFK NYHDLQKLYL QNNKI

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    LGR7 (NP_067647, 68 a.a. ~ 162 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Jelinic, Leo, Post Uiterweer, Sandow, Gooi, Wlodek, Conrad, Parkington, Tare, Parry: "Localization of relaxin receptors in arteries and veins, and region-specific increases in compliance and bradykinin-mediated relaxation after in vivo serelaxin treatment." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 1, pp. 275-87, (2014) (PubMed).

    Ferlin, Menegazzo, Gianesello, Selice, Foresta: "Effect of relaxin on human sperm functions." in: Journal of andrology, Vol. 33, Issue 3, pp. 474-82, (2012) (PubMed).

    Soh, Tiwari, Mahendroo, Conrad, Parry: "Relaxin regulates hyaluronan synthesis and aquaporins in the cervix of late pregnant mice." in: Endocrinology, Vol. 153, Issue 12, pp. 6054-64, (2012) (PubMed).

    Vandevoort, Mtango, Latham, Stewart: "Primate preimplantation embryo is a target for relaxin during early pregnancy." in: Fertility and sterility, Vol. 96, Issue 1, pp. 203-7, (2011) (PubMed).

    Ferlin, Pepe, Facciolli, Gianesello, Foresta: "Relaxin stimulates osteoclast differentiation and activation." in: Bone, Vol. 46, Issue 2, pp. 504-13, (2010) (PubMed).

    Vodstrcil, Shynlova, Verlander, Wlodek, Parry: "Decreased expression of the rat myometrial relaxin receptor (RXFP1) in late pregnancy is partially mediated by the presence of the conceptus." in: Biology of reproduction, Vol. 83, Issue 5, pp. 818-24, (2010) (PubMed).

    Feng, Agoulnik, Truong, Li, Creighton, Kaftanovskaya, Pereira, Han, Lopez-Berestein, Klonisch, Ittmann, Sood, Agoulnik: "Suppression of relaxin receptor RXFP1 decreases prostate cancer growth and metastasis." in: Endocrine-related cancer, Vol. 17, Issue 4, pp. 1021-33, (2010) (PubMed).

    Kern, Bryant-Greenwood: "Characterization of relaxin receptor (RXFP1) desensitization and internalization in primary human decidual cells and RXFP1-transfected HEK293 cells." in: Endocrinology, Vol. 150, Issue 5, pp. 2419-28, (2009) (PubMed).

  • 抗原

    RXFP1 (Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1))

    别名

    RXFP1

    背景

    Full Gene Name: relaxin/insulin-like family peptide receptor 1
    Synonyms: LGR7,LGR7.1,LGR7.10,LGR7.2,MGC138347,MGC142177,RXFPR1

    基因ID

    59350

    NCBI登录号

    NM_021634

    途径

    Myometrial Relaxation and Contraction
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