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ABHD5 抗体 (AA 1-349)

This anti-ABHD5 antibody is a 小鼠 单克隆 antibody detecting ABHD5 in WB, ELISA 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 11+ publications.
产品编号 ABIN565526
发货至: 中国

Quick Overview for ABHD5 抗体 (AA 1-349) (ABIN565526)

抗原

See all ABHD5 抗体
ABHD5 (Abhydrolase Domain Containing 5 (ABHD5))

适用

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宿主

  • 29
  • 5
  • 1
小鼠

克隆类型

  • 28
  • 7
单克隆

标记

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This ABHD5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1F3
  • 抗原表位

    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-349

    原理

    Mouse monoclonal antibody raised against a full length recombinant ABHD5.

    序列

    MAAEEEEVDS ADTGERSGWL TGWLPTWCPT SISHLKEAEE KMLKCVPCTY KKEPVRISNG NKIWTLKFSH NISNKTPLVL LHGFGGGLGL WALNFGDLCT NRPVYAFDLL GFGRSSRPRF DSDAEEVENQ FVESIEEWRC ALGLDKMILL GHNLGGFLAA AYSLKYPSRV NHLILVEPWG FPERPDLADQ DRPIPVWIRA LGAALTPFNP LAGLRIAGPF GLSLVQRLRP DFKRKYSSMF EDDTVTEYIY HCNVQTPSGE TAFKNMTIPY GWAKRPMLQR IGKMHPDIPV SVIFGARSCI DGNSGTSIQS LRPHSYVKTI AILGAGHYVY ADQPEEFNQK VKEICDTVD

    交叉反应

    人, 大鼠

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    ABHD5 (AAH21958, 1 a.a. ~ 349 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Hofer, Boeszoermenyi, Jaeger, Feiler, Arthanari, Mayer, Zehender, Rechberger, Oberer, Zimmermann, Lass, Haemmerle, Breinbauer, Zechner, Preiss-Landl: "Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling." in: The Journal of biological chemistry, Vol. 290, Issue 30, pp. 18438-53, (2015) (PubMed).

    Kurtz, Peck, Fannin, Beysen, Miao, Landstreet, Ding, Turaga, Lund, Turner, Biddinger, Vickers, Sethupathy: "MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes." in: Diabetes, Vol. 63, Issue 9, pp. 3141-8, (2014) (PubMed).

    Patel, Yang, Kozusko, Saudek, Savage: "Perilipins 2 and 3 lack a carboxy-terminal domain present in perilipin 1 involved in sequestering ABHD5 and suppressing basal lipolysis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 25, pp. 9163-8, (2014) (PubMed).

    Camus, Schweiger, Herker, Harris, Kondratowicz, Tsou, Farese, Herath, Previs, Roddy, Pinto, Zechner, Ott et al.: "The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid ..." in: The Journal of biological chemistry, Vol. 289, Issue 52, pp. 35770-80, (2014) (PubMed).

    Pollak, Schweiger, Jaeger, Kolb, Kumari, Schreiber, Kolleritsch, Markolin, Grabner, Heier, Zierler, Rülicke, Zimmermann, Lass, Zechner, Haemmerle: "Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier." in: Journal of lipid research, Vol. 54, Issue 4, pp. 1092-102, (2013) (PubMed).

    Guo, Ma, Kadegowda, Betters, Xie, Liu, Liu, Miao, Ou, Su, Zheng, Xue, Shi, Yu: "Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice." in: Journal of lipid research, Vol. 54, Issue 8, pp. 2109-20, (2013) (PubMed).

    Louche, Badin, Montastier, Laurens, Bourlier, de Glisezinski, Thalamas, Viguerie, Langin, Moro: "Endurance exercise training up-regulates lipolytic proteins and reduces triglyceride content in skeletal muscle of obese subjects." in: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 12, pp. 4863-71, (2013) (PubMed).

    Inoue, Kobayashi, Inoguchi, Sonoda, Maeda, Hirata, Fujimura, Miura, Hirano, Takayanagi: "Downregulation of adipose triglyceride lipase in the heart aggravates diabetic cardiomyopathy in db/db mice." in: Biochemical and biophysical research communications, Vol. 438, Issue 1, pp. 224-9, (2013) (PubMed).

    Grall, Guaguère, Planchais, Grond, Bourrat, Hausser, Hitte, Le Gallo, Derbois, Kim, Lagoutte, Degorce-Rubiales, Radner, Thomas, Küry, Bensignor, Fontaine, Pin, Zimmermann, Zechner, Lathrop, Galibert et al.: "PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans. ..." in: Nature genetics, Vol. 44, Issue 2, pp. 140-7, (2012) (PubMed).

    Stenson, Rydén, Venteclef, Dahlman, Pettersson, Mairal, Aström, Blomqvist, Wang, Jocken, Clément, Langin, Arner, Laurencikiene: "Liver X receptor (LXR) regulates human adipocyte lipolysis." in: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 370-9, (2011) (PubMed).

    Kinney, Qiao, Levaugh, Shao: "B56alpha/protein phosphatase 2A inhibits adipose lipolysis in high-fat diet-induced obese mice." in: Endocrinology, Vol. 151, Issue 8, pp. 3624-32, (2010) (PubMed).

  • 抗原

    ABHD5 (Abhydrolase Domain Containing 5 (ABHD5))

    别名

    ABHD5

    背景

    Full Gene Name: abhydrolase domain containing 5
    Synonyms: CDS,CGI58,IECN2,MGC8731,NCIE2

    基因ID

    51099

    途径

    Lipid Metabolism
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