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TRIB2 抗体 (AA 254-343)

Cited in 3+ publications. This 小鼠 单克隆 anti-TRIB2 antibody (Clone 1B1) specifically detects TRIB2 in WB, ELISA, IHC (p) 和 RNAi. The antibody is reactive with 人 samples.
产品编号 ABIN565396
发货至: 中国
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中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TRIB2 抗体 (AA 254-343) (ABIN565396)

抗原

See all TRIB2 抗体
TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TRIB2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

克隆位点

1B1
  • 抗原表位

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    AA 254-343

    原理

    Mouse monoclonal antibody raised against a partial recombinant TRIB2.

    序列

    FHDIEPSSLF SKIRRGQFNI PETLSPKAKC LIRSILRREP SERLTSQEIL DHPWFSTDFS VSNSAYGAKE VSDQLVPDVN MEENLDPFFN

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    TRIB2 (NP_067675, 254 a.a. ~ 343 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Xu, Tong, Huang, Zhang, Qiao, Weng, Liu, Wang, Sun: "TRIB2 inhibits Wnt/?-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, ?-TrCP, COP1 and Smurf1, in liver cancer cells." in: FEBS letters, Vol. 588, Issue 23, pp. 4334-41, (2014) (PubMed).

    Wang, Zhang, Weng, Qiao, Ma, Xiao, Yu, Pan, Sun et al.: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).

    Qiao, Zhang, Wang: "Ubiquitin E3 ligase SCF(?-TRCP) regulates TRIB2 stability in liver cancer cells." in: Biochemical and biophysical research communications, Vol. 441, Issue 3, pp. 555-9, (2013) (PubMed).

  • 抗原

    TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

    别名

    TRIB2

    背景

    Full Gene Name: tribbles homolog 2 (Drosophila)
    Synonyms: C5FW,GS3955,TRB2

    基因ID

    28951

    NCBI登录号

    NM_021643
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