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BRMS1 抗体 (AA 1-246)

Name: BRMS1 抗体 (AA 1-246)
SKU: ABIN565191
Availability: OutOfStock

This anti-BRMS1 antibody is a 小鼠单克隆 antibody detecting BRMS1 in WB, ELISA 和 IP. Suitable for 人. This Primary Antibody has been cited in 8+ publications.

BRMS1 monoclonal antibody (M01), clone 2D4-2G11. (BRMS1 抗体 (AA 1-246))

Detection limit for recombinant GST tagged BRMS1 is approximately 3ng/ml as a capture antibody. (BRMS1 抗体 (AA 1-246))

ELISA

Immunoprecipitation of BRMS1 transfected lysate using anti-BRMS1 monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with BRMS1 MaxPab rabbit polyclonal antibody. (BRMS1 抗体 (AA 1-246))

Western Blot analysis of BRMS1 expression in transfected 293T cell line by BRMS1 monoclonal antibody (M01), clone 2D4-2G11. (BRMS1 抗体 (AA 1-246))

Western Blot detection against Immunogen (52. (BRMS1 抗体 (AA 1-246))

5 images

(8 references)

产品编号 ABIN565191

发货至: 中国

Datasheet as PDF

Quick Overview for BRMS1 抗体 (AA 1-246) (ABIN565191)

抗原

See all BRMS1 抗体

BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This BRMS1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunoprecipitation (IP)

克隆位点

2D4-2G11

抗原表位
15

8

5

3

3

2

1

1

1

1

1
AA 1-246

原理

Mouse monoclonal antibody raised against a full length recombinant BRMS1.

序列

MPVQPPSKDT EEMEAEGDSA AEMNGEEEES EEERSGSQTE SEEESSEMDD EDYERRRSEC VSEMLDLEKQ FSELKEKLFR ERLSQLRLRL EEVGAERAPE YTEPLGGLQR SLKIRIQVAG IYKGFCLDVI RNKYECELQG AKQHLESEKL LLYDTLQGEL QERIQRLEED RQSLDLSSEW WDDKLHARGS SRSWDSLPPS KRKKAPLVSG PYIVYMLQEI DILEDWTAIK KARAAVSPQK RKSDGP

交叉反应

人

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

BRMS1 (AAH09834, 1 a.a. ~ 246 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

亚型

IgG1
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 90-210) antibody
BRMS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (N-Term) antibody
BRMS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) antibody
BRMS1 适用: 人 IHC 宿主: 兔 Monoclonal unconjugated

anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 48-77), (N-Term) antibody
BRMS1 适用: 人 WB 宿主: 兔 Polyclonal RB40250 unconjugated

anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (C-Term) antibody
BRMS1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 21-70) antibody
BRMS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 1-246) antibody
BRMS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 1-246) antibody
BRMS1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (Center) antibody
BRMS1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) antibody
KD Validated BRMS1 适用: 人 WB, IHC, IP, IF, ICC 宿主: 兔 Monoclonal unconjugated Recombinant Antibody

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Ventura, Quezada, Maloney, Fernandes, Antecka, Martins, Bakalian, di Cesare, Burnier: "Expression of the metastasis suppressor BRMS1 in uveal melanoma." in: Ecancermedicalscience, Vol. 8, pp. 410, (2014) (PubMed).

Liu, Mayo, Nagji, Hall, Shock, Xiao, Stelow, Jones: "BRMS1 suppresses lung cancer metastases through an E3 ligase function on histone acetyltransferase p300." in: Cancer research, Vol. 73, Issue 4, pp. 1308-17, (2013) (PubMed).

Cui, Liu, He, Li, Huang, Sun, Tang, Chen, Jiang, Chen, Yun, Zeng, Guo, Wang, Ma: "Low BRMS1 expression promotes nasopharyngeal carcinoma metastasis in vitro and in vivo and is associated with poor patient survival." in: BMC cancer, Vol. 12, pp. 376, (2012) (PubMed).

Kim, Nam, Pyo, Jang, Kim, Kim, Boo, Lee, Yoon, Baek, Kim: "Breast cancer metastasis suppressor 1 (BRMS1) is destabilized by the Cul3-SPOP E3 ubiquitin ligase complex." in: Biochemical and biophysical research communications, Vol. 415, Issue 4, pp. 720-6, (2011) (PubMed).

Nagji, Liu, Stelow, Stukenborg, Jones: "BRMS1 transcriptional repression correlates with CpG island methylation and advanced pathological stage in non-small cell lung cancer." in: The Journal of pathology, Vol. 221, Issue 2, pp. 229-37, (2010) (PubMed).

Smith, Liu, Siefert, Moskaluk, Petroni, Jones: "Breast cancer metastasis suppressor 1 (BRMS1) suppresses metastasis and correlates with improved patient survival in non-small cell lung cancer." in: Cancer letters, Vol. 276, Issue 2, pp. 196-203, (2009) (PubMed).

Rivera, Megias, Bravo: "Proteomics-based strategy to delineate the molecular mechanisms of the metastasis suppressor gene BRMS1." in: Journal of proteome research, Vol. 6, Issue 10, pp. 4006-18, (2007) (PubMed).

Liu, Smith, Jones: "Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis." in: Molecular and cellular biology, Vol. 26, Issue 23, pp. 8683-96, (2006) (PubMed).
抗原

BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

别名

BRMS1

背景

Full Gene Name: breast cancer metastasis suppressor 1
Synonyms: DKFZp564A063

基因ID

25855