WWP1 抗体 (AA 152-260)
Quick Overview for WWP1 抗体 (AA 152-260) (ABIN564794)
抗原
See all WWP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 152-260
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原理
- Mouse monoclonal antibody raised against a partial recombinant WWP1.
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序列
- CSSSPTIEIQ ENGDALHENG EPSARTTARL AVEGTNGIDN HVPTSTLVQN SCCSYVVNGD NTPSSPSQVA ARPKNTPAPK PLASEPADDT VNGESSSFAP TDNASVTGT
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交叉反应
- 人
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产品特性
- Antibody Reactive Against Recombinant Protein.
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免疫原
- WWP1 (NP_008944, 152 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- In 1x PBS, pH 7.4
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注意事项
- Aliquot to avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis." in: Journal of molecular and cellular cardiology, Vol. 88, pp. 1-13, (2015) (PubMed).
: "Knockdown of WWP1 inhibits growth and induces apoptosis in hepatoma carcinoma cells through the activation of caspase3 and p53." in: Biochemical and biophysical research communications, Vol. 448, Issue 3, pp. 248-54, (2014) (PubMed).
: "WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ?Np73 levels." in: Molecular and cellular biology, Vol. 34, Issue 19, pp. 3754-64, (2014) (PubMed).
: "WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts." in: The Journal of biological chemistry, Vol. 286, Issue 38, pp. 33447-56, (2011) (PubMed).
: "The E3 ubiquitin ligase WWP1 regulates ?Np63-dependent transcription through Lys63 linkages." in: Biochemical and biophysical research communications, Vol. 402, Issue 2, pp. 425-30, (2010) (PubMed).
: "Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5." in: The Biochemical journal, Vol. 423, Issue 1, pp. 31-9, (2009) (PubMed).
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Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis." in: Journal of molecular and cellular cardiology, Vol. 88, pp. 1-13, (2015) (PubMed).
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- WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
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别名
- WWP1
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背景
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Full Gene Name: WW domain containing E3 ubiquitin protein ligase 1
Synonyms: AIP5,DKFZp434D2111,Tiul1,hSDRP1 -
基因ID
- 11059
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NCBI登录号
- NM_007013
抗原
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