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WWP1 抗体 (AA 152-260)

Name: WWP1 抗体 (AA 152-260)
SKU: ABIN564794
Availability: OutOfStock

Cited in 6+ publications. This 小鼠单克隆 anti-WWP1 antibody (Clone 1A7) specifically detects WWP1 in WB, ELISA, IP, IF 和 IHC (p). The antibody is reactive with 人 samples.

Western Blot analysis of WWP1 expression in transfected 293T cell line by WWP1 monoclonal antibody (M01), clone 1A7. (WWP1 抗体 (AA 152-260))

Immunoperoxidase of monoclonal antibody to WWP1 on formalin-fixed paraffin-embedded human stomach. (WWP1 抗体 (AA 152-260))

ISt

Immunofluorescence of monoclonal antibody to WWP1 on A-431 cell. (WWP1 抗体 (AA 152-260))

Immunoprecipitation of WWP1 transfected lysate using anti-WWP1 monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with WWP1 MaxPab rabbit polyclonal antibody. (WWP1 抗体 (AA 152-260))

Detection limit for recombinant GST tagged WWP1 is 0. (WWP1 抗体 (AA 152-260))

ELISA

Western Blot detection against Immunogen (37. (WWP1 抗体 (AA 152-260))

6 images

(6 references)

产品编号 ABIN564794

发货至: 中国

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Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for WWP1 抗体 (AA 152-260) (ABIN564794)

抗原

See all WWP1 抗体

WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This WWP1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1A7

抗原表位
3

2

2

2

1

1

1

1

1
AA 152-260

原理

Mouse monoclonal antibody raised against a partial recombinant WWP1.

序列

CSSSPTIEIQ ENGDALHENG EPSARTTARL AVEGTNGIDN HVPTSTLVQN SCCSYVVNGD NTPSSPSQVA ARPKNTPAPK PLASEPADDT VNGESSSFAP TDNASVTGT

交叉反应

人

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

WWP1 (NP_008944, 152 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

亚型

IgG2a
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 1-260) antibody
WWP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) antibody
WWP1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB15820 unconjugated

anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) antibody
WWP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (Internal Region) antibody
WWP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-260) antibody
WWP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B7 unconjugated

anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) antibody
WWP1 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated

anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) antibody
WWP1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-260) antibody
WWP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 1-922) antibody
WWP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-261) antibody
WWP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A7 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Basheer, Harris, Mentrup, Abreha, Thames, Lea, Swing, Copeland, Jenkins, Price, Matesic: "Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis." in: Journal of molecular and cellular cardiology, Vol. 88, pp. 1-13, (2015) (PubMed).

Cheng, Cao, Yuan, Li, Tong: "Knockdown of WWP1 inhibits growth and induces apoptosis in hepatoma carcinoma cells through the activation of caspase3 and p53." in: Biochemical and biophysical research communications, Vol. 448, Issue 3, pp. 248-54, (2014) (PubMed).

Chaudhary, Maddika: "WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ?Np73 levels." in: Molecular and cellular biology, Vol. 34, Issue 19, pp. 3754-64, (2014) (PubMed).

Cao, Xue, Han, Ma, Chen, Tong: "WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts." in: The Journal of biological chemistry, Vol. 286, Issue 38, pp. 33447-56, (2011) (PubMed).

Peschiaroli, Scialpi, Bernassola, El Sherbini, Melino: "The E3 ubiquitin ligase WWP1 regulates ?Np63-dependent transcription through Lys63 linkages." in: Biochemical and biophysical research communications, Vol. 402, Issue 2, pp. 425-30, (2010) (PubMed).

Edwards, Clowes, Tsang, Connell, Sanderson, Luzio, Reid: "Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5." in: The Biochemical journal, Vol. 423, Issue 1, pp. 31-9, (2009) (PubMed).
抗原

WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

别名

WWP1

背景

Full Gene Name: WW domain containing E3 ubiquitin protein ligase 1
Synonyms: AIP5,DKFZp434D2111,Tiul1,hSDRP1

基因ID

11059

NCBI登录号

NM_007013