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WWP1 抗体 (AA 152-260)

This anti-WWP1 antibody is a 小鼠 单克隆 antibody detecting WWP1 in WB, ELISA, IP, IF 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN564794
发货至: 中国

Quick Overview for WWP1 抗体 (AA 152-260) (ABIN564794)

抗原

See all WWP1 抗体
WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

适用

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  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1

宿主

  • 21
  • 4
小鼠

克隆类型

  • 22
  • 3
单克隆

标记

  • 18
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This WWP1 antibody is un-conjugated

应用范围

  • 15
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Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1A7
  • 抗原表位

    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 152-260

    原理

    Mouse monoclonal antibody raised against a partial recombinant WWP1.

    序列

    CSSSPTIEIQ ENGDALHENG EPSARTTARL AVEGTNGIDN HVPTSTLVQN SCCSYVVNGD NTPSSPSQVA ARPKNTPAPK PLASEPADDT VNGESSSFAP TDNASVTGT

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    WWP1 (NP_008944, 152 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Basheer, Harris, Mentrup, Abreha, Thames, Lea, Swing, Copeland, Jenkins, Price, Matesic: "Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis." in: Journal of molecular and cellular cardiology, Vol. 88, pp. 1-13, (2015) (PubMed).

    Cheng, Cao, Yuan, Li, Tong: "Knockdown of WWP1 inhibits growth and induces apoptosis in hepatoma carcinoma cells through the activation of caspase3 and p53." in: Biochemical and biophysical research communications, Vol. 448, Issue 3, pp. 248-54, (2014) (PubMed).

    Chaudhary, Maddika: "WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ?Np73 levels." in: Molecular and cellular biology, Vol. 34, Issue 19, pp. 3754-64, (2014) (PubMed).

    Cao, Xue, Han, Ma, Chen, Tong: "WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts." in: The Journal of biological chemistry, Vol. 286, Issue 38, pp. 33447-56, (2011) (PubMed).

    Peschiaroli, Scialpi, Bernassola, El Sherbini, Melino: "The E3 ubiquitin ligase WWP1 regulates ?Np63-dependent transcription through Lys63 linkages." in: Biochemical and biophysical research communications, Vol. 402, Issue 2, pp. 425-30, (2010) (PubMed).

    Edwards, Clowes, Tsang, Connell, Sanderson, Luzio, Reid: "Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5." in: The Biochemical journal, Vol. 423, Issue 1, pp. 31-9, (2009) (PubMed).

  • 抗原

    WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

    别名

    WWP1

    背景

    Full Gene Name: WW domain containing E3 ubiquitin protein ligase 1
    Synonyms: AIP5,DKFZp434D2111,Tiul1,hSDRP1

    基因ID

    11059

    NCBI登录号

    NM_007013
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