AANAT 抗体 (AA 27-54)
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Quick Overview for AANAT 抗体 (AA 27-54) (ABIN5647916)
抗原
See all AANAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-54
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 27-54 from the human protein was used as the immunogen for this AANAT antibody.
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亚型
- Ig Fraction
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应用备注
- Western blot: 1:1000
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限制
- 仅限研究用
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the AANAT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- AANAT (Aralkylamine N-Acetyltransferase (AANAT))
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别名
- AANAT
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背景
- Serotonin N-acetyltransferase/AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.
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UniProt
- Q16613
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途径
- Photoperiodism
抗原
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