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PVRL4 抗体 (AA 53-94)

The 兔 多克隆 anti-PVRL4 antibody is suitable to detect PVRL4 in samples from 人. It has been validated for WB.
产品编号 ABIN5647906
发货至: 中国
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Quick Overview for PVRL4 抗体 (AA 53-94) (ABIN5647906)

抗原

See all PVRL4 抗体
PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

适用

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宿主

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克隆类型

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多克隆

标记

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This PVRL4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 53-94

    纯化方法

    Antigen affinity purified

    免疫原

    Amino acids 53-94 (FYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAY) from the human protein were used as the immunogen for the Nectin-4 antibody.

    亚型

    IgG
  • 应用备注

    Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Nectin-4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

    别名

    Nectin-4 / PVRL4

    背景

    PVRL4, also known as Nectin-4, is expressed in human skin, hair follicles, and cultured keratinocytes, but not in fibroblasts. This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

    UniProt

    Q96NY8

    途径

    Cell-Cell Junction Organization
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