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12-Lipoxygenase 抗体 (AA 186-231)

LOX12 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647834
发货至: 中国
  • 抗原 See all 12-Lipoxygenase (LOX12) products
    12-Lipoxygenase (LOX12)
    抗原表位
    AA 186-231
    适用
    人, 小鼠, 大鼠
    宿主
    • 1
    克隆类型
    • 1
    多克隆
    标记
    • 1
    This 12-Lipoxygenase antibody is un-conjugated
    应用范围
    Western Blotting (WB)
    纯化方法
    Antigen affinity purified
    免疫原
    Amino acids 186-231 (ALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFSYQ) from the human protein were used as the immunogen for the 12 Lipoxygenase antibody.
    亚型
    IgG
  • 应用备注
    Optimal dilution of the 12 Lipoxygenase antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the 12 Lipoxygenase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    12-Lipoxygenase (LOX12)
    别名
    12 Lipoxygenase (LOX12 产品)
    别名
    12-LOX antibody, 12S-LOX antibody, LOG12 antibody, wu:fi89d03 antibody, zgc:153926 antibody, arachidonate 12-lipoxygenase, 12S type antibody, zgc:152891 antibody, ALOX12 antibody, zgc:152891 antibody
    背景
    ALOX12 (Arachidonate 12-lipoxygenase) is an enzyme that in humans is encoded by the ALOX12 gene. By fluorescence in situ hybridization, the gene is located in band 17p13.1. The gene consists of 14 exons with 13 introns and spans approximately 15 kb of DNA Arachidonate 12-lipoxygenase introduces a molecular oxygen into the C-12 position of arachidonic acid to produce 12(S)-hydroperoxy-5,8,10,14-eicosatetraenoic acid. The major pathway of arachidonic acid metabolism in human platelets proceeds via a 12-lipoxygenase enzyme. Expression of the LOG12 gene was detected in human erythroleukemia cells, platelets, and human umbilical vein endothelial cells by reverse transcription-PCR analysis.
    UniProt
    P18054
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