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KRIT1 抗体 (AA 703-736)

KRIT1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647767
发货至: 中国
  • 抗原 See all KRIT1 抗体
    KRIT1 (KRIT1, Ankyrin Repeat Containing (KRIT1))
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 703-736
    适用
    人, 小鼠, 大鼠
    宿主
    • 39
    • 4
    克隆类型
    • 39
    • 4
    多克隆
    标记
    • 15
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KRIT1 antibody is un-conjugated
    应用范围
    • 36
    • 22
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity purified
    免疫原
    Amino acids 703-736 (ENKMSFIVHTKQAGLVVKLLMKLNGQLMPTERNS) from the human protein were used as the immunogen for the KRIT1 antibody.
    亚型
    IgG
    Top Product
    Discover our top product KRIT1 Primary Antibody
  • 应用备注
    Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the KRIT1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    KRIT1 (KRIT1, Ankyrin Repeat Containing (KRIT1))
    别名
    KRIT1 (KRIT1 产品)
    别名
    CAM antibody, CCM1 antibody, 2010007K12Rik antibody, A630036P20Rik antibody, AA432855 antibody, AI450393 antibody, AI643869 antibody, BB155247 antibody, BB235701 antibody, Ccm1 antibody, RGD1305929 antibody, krit1 antibody, fb36f07 antibody, san antibody, santa antibody, wu:fb36f07 antibody, zgc:63585 antibody, KRIT1, ankyrin repeat containing antibody, KRIT1 antibody, Krit1 antibody, krit1 antibody
    背景
    Krev interaction trapped protein 1 is a protein that in humans is encoded by the CCM1 gene. This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene.
    UniProt
    O00522
    途径
    Cell RedoxHomeostasis
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