GLA 抗体 (AA 218-275)
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Quick Overview for GLA 抗体 (AA 218-275) (ABIN5647751)
抗原
See all GLA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 218-275
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 218-275 (DIQYYCNHWRNFDDVYDSWESIKNILSWTVVYQKEIVEVA-mouse) were used as the immunogen for the Gla antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Gla antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Gla antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- GLA (Galactosidase, alpha (GLA))
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别名
- Gla / Galactosidase alpha
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背景
- Alpha-galactosidase is a glycoside hydrolase enzyme that encoded by the GLA gene. This gene is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
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UniProt
- P51569
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途径
- SARS-CoV-2 Protein Interactome
抗原
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