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ASXL1 抗体

ASXL1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647693
发货至: 中国
  • 抗原 See all ASXL1 抗体
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    适用
    • 27
    • 24
    • 1
    人, 小鼠
    宿主
    • 29
    • 2
    克隆类型
    • 29
    • 2
    多克隆
    标记
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASXL1 antibody is un-conjugated
    应用范围
    • 22
    • 16
    • 14
    • 14
    • 14
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity purified
    免疫原
    Amino acids KKERTWAEAARLVLENYSDAPMTPKQILQVIEAE were used as the immunogen for the ASXL1 antibody.
    亚型
    IgG
    Top Product
    Discover our top product ASXL1 Primary Antibody
  • 应用备注
    Optimal dilution of the ASXL1 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the ASXL1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    别名
    ASXL1 (ASXL1 产品)
    背景
    Putative Polycomb group protein ASXL1 is a protein that in humans is encoded by the ASXL1 gene. This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.
    UniProt
    Q8IXJ9
    途径
    Retinoic Acid Receptor Signaling Pathway
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