VASP 抗体 (AA 78-114)
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Quick Overview for VASP 抗体 (AA 78-114) (ABIN5647624)
抗原
See all VASP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 78-114
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 78-114 (NFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALE-human) were used as the immunogen for this VASP antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the VASP antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the VASP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
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别名
- VASP
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背景
- Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
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UniProt
- P50552
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途径
- TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
抗原
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