CCL17 抗体 (AA 553-582)
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Quick Overview for CCL17 抗体 (AA 553-582) (ABIN5647610)
抗原
See all CCL17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 553-582
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 553-582 from the human protein was used as the immunogen for this ABCD2 antibody.
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亚型
- Ig Fraction
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应用备注
- Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ABCD2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))
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别名
- ABCD2
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背景
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown, however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.
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UniProt
- Q9UBJ2
抗原
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