FGA 抗体 (AA 687-727)
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Quick Overview for FGA 抗体 (AA 687-727) (ABIN5647558)
抗原
See all FGA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 687-727
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交叉反应 (详细)
- Expected species reactivity: Mouse
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 687-727 (RTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSVLRVE-human) were used as the immunogen for the Fibrinogen alpha chain antibody. This sequence is specific to the alpha-E isoform and not found in the alpha isoform.
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亚型
- IgG
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应用备注
- Optimal dilution of the Fibrinogen alpha chain antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Fibrinogen alpha chain antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- FGA (Fibrinogen alpha Chain (FGA))
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背景
- Fibrinogen alpha chain is a protein that in humans is encoded by the FGA gene. This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing.
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UniProt
- P02671
抗原
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