CYP17A1 抗体 (AA 383-419)
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Quick Overview for CYP17A1 抗体 (AA 383-419) (ABIN5647530)
抗原
See all CYP17A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 383-419
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 383-419 (EFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLN-human) were used as the immunogen for the CYP17A1 antibody.
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亚型
- IgG
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anti-Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) (AA 24-65) antibody
CYP17A1 适用: 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) (AA 1-508) antibodyCYP17A1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) (Internal Region) antibodyCYP17A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) (AA 24-508) antibodyCYP17A1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) (AA 201-507) antibodyCYP17A1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) (AA 201-507) antibodyCYP17A1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) antibodyCYP17A1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Monoclonal 5A9 unconjugated Recombinant Antibody
anti-Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) (Center) antibodyCYP17A1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) (AA 209-508) antibodyCYP17A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) (Internal Region) antibodyVerified CYP17A1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal dilution of the CYP17A1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the CYP17A1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))
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别名
- CYP17A1
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背景
- Cytochrome P450 17A1, also called steroid 17< font face=symbol>a-monooxygenase, is an enzyme of the hydroxylase type that in humans is encoded by the CYP17A1 gene on chromosome 10. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
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UniProt
- P05093
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途径
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin
抗原
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