ACCN1 抗体 (AA 112-147)
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Quick Overview for ACCN1 抗体 (AA 112-147) (ABIN5647475)
抗原
See all ACCN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 112-147
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 112-147 (ELLALLDVNLQIPDPHLADPSVLEALRQKANFKHYK from the human protein were used as the immunogen for the ACCN1 antibody.
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亚型
- IgG
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应用备注
- Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the ACCN1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))
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别名
- ACCN1 / ASIC2
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背景
- Amiloride-sensitive cation channel 1, neuronal, also known as ASIC2, is a protein that in humans is encoded by the ACCN1 gene. This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.
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UniProt
- Q16515
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途径
- Sensory Perception of Sound
抗原
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