HTRA3 抗体 (AA 330-362)
Our Local Distributor
北京 101111
Quick Overview for HTRA3 抗体 (AA 330-362) (ABIN5647345)
抗原
See all HTRA3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 330-362
-
纯化方法
- Antigen affinity purified
-
免疫原
- Amino acids 330-362 (FAIPSDRITRFLTEFQDKQIKDWKKRFIGIRMR) from the human protein were used as the immunogen for the HtrA3 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the HtrA3 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL
-
限制
- 仅限研究用
-
-
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- -20 °C
-
储存方法
- After reconstitution, the HtrA3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
-
- HTRA3 (HtrA Serine Peptidase 3 (HTRA3))
-
别名
- HtrA3
-
背景
- Human HtrA3 protease, which induces mitochondria-mediated apoptosis, can be a tumor suppressor and a potential therapeutic target in the treatment of cancer. It may also have a role in ovarian development, granulosa cell differentiation and luteinization. The long isoform, HTRA3L, contains 453 amino acids and has a predicted molecular mass of 49 kD. It contains an N-terminal signal peptide, followed by an insulin/IGF (see 147440)-binding domain, a Kazal-type S protease inhibitor domain, a trypsin protease domain, and a PDZ domain. The short isoform, HTRA3S, contains 357 amino acids and has a predicted molecular mass of 38 kD.
-
UniProt
- P83110
抗原
-