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SAFB 抗体 (AA 715-754)

SAFB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647265
发货至: 中国
  • 抗原 See all SAFB 抗体
    SAFB (Scaffold Attachment Factor B (SAFB))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 715-754
    适用
    • 39
    • 22
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 44
    • 10
    克隆类型
    • 43
    • 11
    多克隆
    标记
    • 30
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SAFB antibody is un-conjugated
    应用范围
    • 37
    • 21
    • 14
    • 14
    • 13
    • 12
    • 9
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity purified
    免疫原
    Amino acids 715-754 (DLDRRDDAYWPEAKRAALDERYHSDFNRQDRFHDFDHRDR) from the human protein were used as the immunogen for the SAFB antibody.
    亚型
    IgG
    Top Product
    Discover our top product SAFB Primary Antibody
  • 应用备注
    Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the SAFB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    SAFB (Scaffold Attachment Factor B (SAFB))
    别名
    SAFB / Scaffold attachment factor B1 (SAFB 产品)
    别名
    HAP antibody, HET antibody, SAF-B1 antibody, SAFB1 antibody, 3110021E02Rik antibody, 5330423C17Rik antibody, AU018122 antibody, D18386 antibody, E130307D12 antibody, zgc:55387 antibody, wu:fb40a03 antibody, wu:fd42g06 antibody, SAFB2 antibody, SAFB antibody, scaffold attachment factor B antibody, scaffold attachment factor B S homeolog antibody, SAFB-like transcription modulator antibody, Scaffold attachment factor B antibody, SAFB antibody, Safb antibody, safb antibody, safb.S antibody, LOC5570070 antibody, CpipJ_CPIJ017179 antibody, Bm1_49330 antibody, LOAG_00080 antibody
    背景
    Scaffold attachment factor B, also known as SAFB, is a gene with homologs that have been studied in humans and mice. This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.
    UniProt
    Q15424
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway
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