SAFB 抗体 (AA 715-754)
Quick Overview for SAFB 抗体 (AA 715-754) (ABIN5647265)
抗原
See all SAFB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 715-754
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 715-754 (DLDRRDDAYWPEAKRAALDERYHSDFNRQDRFHDFDHRDR) from the human protein were used as the immunogen for the SAFB antibody.
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亚型
- IgG
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anti-Scaffold Attachment Factor B (SAFB) antibody
SAFB 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Scaffold Attachment Factor B (SAFB) (AA 1-200) antibodySAFB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Scaffold Attachment Factor B (SAFB) antibodySAFB 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Scaffold Attachment Factor B (SAFB) (AA 111-200) antibodySAFB 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5A11 unconjugated
anti-Scaffold Attachment Factor B (SAFB) (AA 111-201) antibodySAFB 适用: 人 WB, IHC, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5A11 unconjugated
anti-Scaffold Attachment Factor B (SAFB) (AA 300-400) antibodySAFB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Scaffold Attachment Factor B (SAFB) (C-Term) antibodySAFB 适用: 人, 小鼠, 兔 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the SAFB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- SAFB (Scaffold Attachment Factor B (SAFB))
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别名
- SAFB / Scaffold attachment factor B1
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背景
- Scaffold attachment factor B, also known as SAFB, is a gene with homologs that have been studied in humans and mice. This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q15424
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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