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PON1 抗体

This anti-PON1 antibody is a 兔 多克隆 antibody detecting PON1 in WB, IHC (p) 和 ELISA (Capture). Suitable for 小鼠 和 大鼠.
产品编号 ABIN5647230
发货至: 中国

Quick Overview for PON1 抗体 (ABIN5647230)

抗原

See all PON1 抗体
PON1 (Paraoxonase 1 (PON1))

适用

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  • 1
小鼠, 大鼠

宿主

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  • 1

克隆类型

  • 96
  • 19
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This PON1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA (Capture)
  • 纯化方法

    Antigen affinity purified

    免疫原

    A recombinant mouse protein corresponding to amino acids A30-D274 was used as the immunogen for the PON1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the PON1 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,ELISA (Capture, mouse recombinant protein): 0.1-0.5 μg/mL (BSA-free format available)

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the PON1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    PON1 (Paraoxonase 1 (PON1))

    别名

    PON1

    背景

    Serum paraoxonase/arylesterase 1 (PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-?, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis.

    UniProt

    P52430
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