Western blot: 1:500-1:1000,IHC (FFPE): 1:50-100,Immunofluorescence: 1:100
限制
仅限研究用
缓冲液
In 1X PBS, pH 7.4, with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the PACSIN2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原
PACSIN2
(Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2))
别名
PACSIN2
背景
Protein kinase C and casein kinase substrate in neurons protein 2 is a lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle- mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.