Oncostatin M 抗体
Quick Overview for Oncostatin M 抗体 (ABIN5647222)
抗原
See all Oncostatin M (OSM) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity purified
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免疫原
- A recombinant mouse protein corresponding to amino acids N25-R206 was used as the immunogen for the Oncostatin M antibody.
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亚型
- IgG
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anti-Oncostatin M (OSM) (AA 116-205) antibody
OSM 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) antibodyOSM 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Oncostatin M (OSM) (AA 26-220) antibodyOSM 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) (AA 25-115) antibodyOSM 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) (AA 26-252) antibodyOSM 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) (AA 26-220) antibodyOSM 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) (AA 1-252) antibodyOSM 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) (AA 1-252) antibodyOSM 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) (AA 181-198), (Middle Region) antibodyOSM 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) (AA 26-207) antibodyOSM 适用: 大鼠 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Oncostatin M antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (capture): 0.1-0.5 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Oncostatin M antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Oncostatin M (OSM)
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别名
- Oncostatin M / OSM
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背景
- OSM (Oncostatin M) is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is mapped on 22q12.2. It has the ability to inhibit the growth of human A375 melanoma cells but not normal human fibroblasts. Treatment with recombinant OSM leads to the inhibition of proliferation and changes in cellular morphology of a number of tumor cell lines derived from a wide variety of tissue types. OSM also has the ability to inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells, a function shared by LIF, CSF3, and IL6. The direction of gene transcription was telomeric to centromeric, with the OSM gene located upstream of the LIF gene.
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UniProt
- P53347
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途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
抗原
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