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RANBP2 抗体 (AA 3018-3057)

RANBP2 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647220
发货至: 中国
  • 抗原 See all RANBP2 抗体
    RANBP2 (RAN Binding Protein 2 (RANBP2))
    抗原表位
    • 5
    • 2
    • 1
    • 1
    AA 3018-3057
    适用
    • 26
    • 18
    • 17
    • 1
    小鼠, 大鼠
    宿主
    • 26
    克隆类型
    • 26
    多克隆
    标记
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RANBP2 antibody is un-conjugated
    应用范围
    • 13
    • 8
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    交叉反应 (详细)
    Expected species reactivity: Human
    纯化方法
    Antigen affinity purified
    免疫原
    Amino acids 3018-3057 (EQLAVRFKTKEVADCFKKTFEECQQNLMKLQKGHVSLAAE) were used as the immunogen for the RanBP2 antibody.
    亚型
    IgG
    Top Product
    Discover our top product RANBP2 Primary Antibody
  • 应用备注
    Optimal dilution of the RanBP2 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the RanBP2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    RANBP2 (RAN Binding Protein 2 (RANBP2))
    别名
    RanBP2 (RANBP2 产品)
    别名
    ANE1 antibody, IIAE3 antibody, NUP358 antibody, TRP1 antibody, TRP2 antibody, A430087B05Rik antibody, AI256741 antibody, RGD1560047 antibody, RANBP2 antibody, ane1 antibody, nup358 antibody, trp1 antibody, trp2 antibody, RAN binding protein 2 antibody, E3 SUMO-protein ligase RanBP2 antibody, RANBP2 antibody, Ranbp2 antibody, LOC474539 antibody, ranbp2 antibody, LOC100511376 antibody
    背景
    RAN binding protein 2 (RANBP2), also called NUP358 is protein which in humans is encoded by the RANBP2 gene. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. And the encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q.
    UniProt
    P49792
    途径
    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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