RANBP2 抗体 (AA 3018-3057)
Quick Overview for RANBP2 抗体 (AA 3018-3057) (ABIN5647220)
抗原
See all RANBP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3018-3057
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交叉反应 （详细）
- Expected species reactivity: Human
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 3018-3057 (EQLAVRFKTKEVADCFKKTFEECQQNLMKLQKGHVSLAAE) were used as the immunogen for the RanBP2 antibody.
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亚型
- IgG
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anti-RAN Binding Protein 2 (RANBP2) antibody
RANBP2 适用: 人, 小鼠, 大鼠 ELISA, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 2 (RANBP2) (AA 2601-2802) antibodyRANBP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 2 (RANBP2) (AA 1050-1100) antibodyRANBP2 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the RanBP2 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the RanBP2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- RANBP2 (RAN Binding Protein 2 (RANBP2))
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别名
- RanBP2
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背景
- RAN binding protein 2 (RANBP2), also called NUP358 is protein which in humans is encoded by the RANBP2 gene. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. And the encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q.
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UniProt
- P49792
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途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
抗原
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