PNP 抗体 (AA 161-189)
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Quick Overview for PNP 抗体 (AA 161-189) (ABIN5647213)
抗原
See all PNP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-189
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 161-189 (AMSDAYDRTMRQRALSTWKQMGEQRELQE-human) were used as the immunogen for the Purine nucleoside phosphorylase antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Purine nucleoside phosphorylase antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL,Flow cytometry: 1-3 μg/10^6 cells
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Purine nucleoside phosphorylase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- PNP (Purine Nucleoside Phosphorylase (PNP))
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别名
- PNP / Purine Nucleoside Phosphorylase
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背景
- The PNP gene encodes Purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.
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UniProt
- P00491
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
抗原
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