Muscarinic Acetylcholine Receptor M2 抗体 (AA 352-376)
Quick Overview for Muscarinic Acetylcholine Receptor M2 抗体 (AA 352-376) (ABIN5647209)
抗原
See all Muscarinic Acetylcholine Receptor M2 (CHRM2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 352-376
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交叉反应 (详细)
- Expected species reactivity: Human
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 352-376 (QNGDEKQNIVARKIVKMTKQPAKKK) from the human protein were used as the immunogen for the CHRM2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CHRM2 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the CHRM2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
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别名
- CHRM2
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背景
- The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded by the CHRM2 gene. The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
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UniProt
- P08172
抗原
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