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MXD1 抗体

This anti-MXD1 antibody is a 兔 多克隆 antibody detecting MXD1 in WB 和 ELISA. Suitable for 小鼠 和 大鼠.
产品编号 ABIN5647191
发货至: 中国

Quick Overview for MXD1 抗体 (ABIN5647191)

抗原

See all MXD1 抗体
MXD1 (MAX Dimerization Protein 1 (MXD1))

适用

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小鼠, 大鼠

宿主

  • 20
  • 3

克隆类型

  • 20
  • 3
多克隆

标记

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This MXD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 交叉反应 (详细)

    Expected species reactivity: Human

    纯化方法

    Antigen affinity purified

    免疫原

    A recombinant human protein corresponding to amino acids M1-L221 was used as the immunogen for the MAD antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the MAD antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the MAD antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    MXD1 (MAX Dimerization Protein 1 (MXD1))

    别名

    MAD / MXD1 / Max dimerization protein 1

    背景

    MAD protein is a protein that in humans is encoded by the MXD1 gene. This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

    UniProt

    Q05195
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