MXD1 抗体
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Quick Overview for MXD1 抗体 (ABIN5647191)
抗原
See all MXD1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应 （详细）
- Expected species reactivity: Human
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纯化方法
- Antigen affinity purified
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免疫原
- A recombinant human protein corresponding to amino acids M1-L221 was used as the immunogen for the MAD antibody.
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亚型
- IgG
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anti-MAX Dimerization Protein 1 (MXD1) (AA 1-221) antibody
MXD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Dimerization Protein 1 (MXD1) (C-Term) antibodyMXD1 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Dimerization Protein 1 (MXD1) (AA 60-149) antibodyMXD1 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G10 unconjugated
anti-MAX Dimerization Protein 1 (MXD1) (AA 60-150) antibodyMXD1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2G10 unconjugated
anti-MAX Dimerization Protein 1 (MXD1) (AA 681-730) antibodyMXD1 适用: 小鼠, Cow, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Dimerization Protein 1 (MXD1) (N-Term) antibodyMXD1 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 犬, 马, 斑马鱼, Bat, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the MAD antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the MAD antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- MXD1 (MAX Dimerization Protein 1 (MXD1))
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别名
- MAD / MXD1 / Max dimerization protein 1
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背景
- MAD protein is a protein that in humans is encoded by the MXD1 gene. This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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UniProt
- Q05195
抗原
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