IL17F 抗体 (AA 29-161)
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北京 101111
Quick Overview for IL17F 抗体 (AA 29-161) (ABIN5647177)
抗原
See all IL17F 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 29-161
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原理
- IL17F Antibody / Interleukin 17F
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纯化方法
- Antigen affinity
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免疫原
- A recombinant mouse protein corresponding to amino acids R29-A161 was used as the immunogen for the IL17F antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the IL17F antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the IL17F antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IL17F (Interleukin 17F (IL17F))
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别名
- IL17F
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背景
- Interleukin 17F, also called IL17F is involved in the regulation of normal versus aberrant T-cell responses. This gene is mapped to 6p12.2. The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. It is suggested that targeting IL17 and IL17F or antagonizing IL17R might mitigate neutrophil-mediated inflammation in CF.
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UniProt
- Q7TNI7
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
抗原
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